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Cryo-EM structure of human rhodopsin bound to an inhibitory G protein
G-protein-coupled receptors comprise the largest family of mammalian transmembrane receptors. They mediate numerous cellular pathways by coupling with downstream signalling transducers, including the hetrotrimeric G proteins G(s) (stimulatory) and G(i) (inhibitory) and several arrestin proteins. The...
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| Vydáno v: | Nature |
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8054211/ https://ncbi.nlm.nih.gov/pubmed/29899450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0215-y |
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