Cryo-EM structure of the native rhodopsin dimer in nanodiscs

Imaging of rod photoreceptor outer-segment disc membranes by atomic force microscopy and cryo-electron tomography has revealed that the visual pigment rhodopsin, a prototypical class A G protein–coupled receptor (GPCR), can organize as rows of dimers. GPCR dimerization and oligomerization offer poss...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhao, Dorothy Yanling, Pöge, Matthias, Morizumi, Takefumi, Gulati, Sahil, Van Eps, Ned, Zhang, Jianye, Miszta, Przemyslaw, Filipek, Slawomir, Mahamid, Julia, Plitzko, Jürgen M., Baumeister, Wolfgang, Ernst, Oliver P., Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768649/
https://ncbi.nlm.nih.gov/pubmed/31399513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010089
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