Conformational equilibria of light-activated rhodopsin in nanodiscs

Conformational equilibria of G-protein–coupled receptors (GPCRs) are intimately involved in intracellular signaling. Here conformational substates of the GPCR rhodopsin are investigated in micelles of dodecyl maltoside (DDM) and in phospholipid nanodiscs by monitoring the spatial positions of transm...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Van Eps, Ned, Caro, Lydia N., Morizumi, Takefumi, Kusnetzow, Ana Karin, Szczepek, Michal, Hofmann, Klaus Peter, Bayburt, Timothy H., Sligar, Stephen G., Ernst, Oliver P., Hubbell, Wayne L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
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PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402410/
https://ncbi.nlm.nih.gov/pubmed/28373559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620405114
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