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Conformational equilibria of light-activated rhodopsin in nanodiscs

Conformational equilibria of G-protein–coupled receptors (GPCRs) are intimately involved in intracellular signaling. Here conformational substates of the GPCR rhodopsin are investigated in micelles of dodecyl maltoside (DDM) and in phospholipid nanodiscs by monitoring the spatial positions of transm...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Van Eps, Ned, Caro, Lydia N., Morizumi, Takefumi, Kusnetzow, Ana Karin, Szczepek, Michal, Hofmann, Klaus Peter, Bayburt, Timothy H., Sligar, Stephen G., Ernst, Oliver P., Hubbell, Wayne L.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402410/
https://ncbi.nlm.nih.gov/pubmed/28373559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620405114
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