Conformational equilibria of light-activated rhodopsin in nanodiscs

Conformational equilibria of G-protein–coupled receptors (GPCRs) are intimately involved in intracellular signaling. Here conformational substates of the GPCR rhodopsin are investigated in micelles of dodecyl maltoside (DDM) and in phospholipid nanodiscs by monitoring the spatial positions of transm...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Van Eps, Ned, Caro, Lydia N., Morizumi, Takefumi, Kusnetzow, Ana Karin, Szczepek, Michal, Hofmann, Klaus Peter, Bayburt, Timothy H., Sligar, Stephen G., Ernst, Oliver P., Hubbell, Wayne L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402410/
https://ncbi.nlm.nih.gov/pubmed/28373559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620405114
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