Conformational equilibria of light-activated rhodopsin in nanodiscs

Conformational equilibria of G-protein–coupled receptors (GPCRs) are intimately involved in intracellular signaling. Here conformational substates of the GPCR rhodopsin are investigated in micelles of dodecyl maltoside (DDM) and in phospholipid nanodiscs by monitoring the spatial positions of transm...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Van Eps, Ned, Caro, Lydia N., Morizumi, Takefumi, Kusnetzow, Ana Karin, Szczepek, Michal, Hofmann, Klaus Peter, Bayburt, Timothy H., Sligar, Stephen G., Ernst, Oliver P., Hubbell, Wayne L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402410/
https://ncbi.nlm.nih.gov/pubmed/28373559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620405114
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