Conformational equilibria of light-activated rhodopsin in nanodiscs

Conformational equilibria of G-protein–coupled receptors (GPCRs) are intimately involved in intracellular signaling. Here conformational substates of the GPCR rhodopsin are investigated in micelles of dodecyl maltoside (DDM) and in phospholipid nanodiscs by monitoring the spatial positions of transm...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Van Eps, Ned, Caro, Lydia N., Morizumi, Takefumi, Kusnetzow, Ana Karin, Szczepek, Michal, Hofmann, Klaus Peter, Bayburt, Timothy H., Sligar, Stephen G., Ernst, Oliver P., Hubbell, Wayne L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2017
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402410/
https://ncbi.nlm.nih.gov/pubmed/28373559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620405114
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