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Osmolyte perturbation reveals conformational equilibria in spin-labeled proteins

Recent evidence suggests that proteins at equilibrium can exist in a manifold of conformational substates, and that these substates play important roles in protein function. Therefore, there is great interest in identifying regions in proteins that are in conformational exchange. Electron paramagnet...

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Bibliografske podrobnosti
Main Authors: López, Carlos J, Fleissner, Mark R, Guo, Zhefeng, Kusnetzow, Ana K, Hubbell, Wayne L
Format: Artigo
Jezik:Inglês
Izdano: Wiley Subscription Services, Inc., A Wiley Company 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776952/
https://ncbi.nlm.nih.gov/pubmed/19585559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.180
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