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Osmolyte perturbation reveals conformational equilibria in spin-labeled proteins

Recent evidence suggests that proteins at equilibrium can exist in a manifold of conformational substates, and that these substates play important roles in protein function. Therefore, there is great interest in identifying regions in proteins that are in conformational exchange. Electron paramagnet...

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Detalhes bibliográficos
Main Authors: López, Carlos J, Fleissner, Mark R, Guo, Zhefeng, Kusnetzow, Ana K, Hubbell, Wayne L
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776952/
https://ncbi.nlm.nih.gov/pubmed/19585559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.180
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