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Osmolyte perturbation reveals conformational equilibria in spin-labeled proteins

Recent evidence suggests that proteins at equilibrium can exist in a manifold of conformational substates, and that these substates play important roles in protein function. Therefore, there is great interest in identifying regions in proteins that are in conformational exchange. Electron paramagnet...

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Hlavní autoři: López, Carlos J, Fleissner, Mark R, Guo, Zhefeng, Kusnetzow, Ana K, Hubbell, Wayne L
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Subscription Services, Inc., A Wiley Company 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776952/
https://ncbi.nlm.nih.gov/pubmed/19585559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.180
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