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Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging
We have previously used cryo-electron tomography combined with sub-volume averaging and classification to obtain 3D structures of macromolecular assemblies in cases where a single dominant species was present, and applied these methods to the analysis of a variety of trimeric HIV-1 and SIV envelope...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3350607/ https://ncbi.nlm.nih.gov/pubmed/22248450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2012.01.004 |
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