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Membrane protein structure determination using cryo-electron tomography and 3D image averaging

The vast majority of membrane protein complexes of biological interest cannot be purified to homogeneity, or removed from a physiologically relevant context without loss of function. It is therefore not possible to easily determine the 3D structures of these protein complexes using X-ray crystallogr...

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Detalhes bibliográficos
Main Authors: Bartesaghi, Alberto, Subramaniam, Sriram
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752674/
https://ncbi.nlm.nih.gov/pubmed/19646859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2009.06.005
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