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Membrane protein structure determination using cryo-electron tomography and 3D image averaging
The vast majority of membrane protein complexes of biological interest cannot be purified to homogeneity, or removed from a physiologically relevant context without loss of function. It is therefore not possible to easily determine the 3D structures of these protein complexes using X-ray crystallogr...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752674/ https://ncbi.nlm.nih.gov/pubmed/19646859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2009.06.005 |
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