Identification of Phosphorylation Codes for Arrestin Recruitment by G protein-Coupled Receptors

G protein-coupled receptors (GPCRs) mediate diverse signaling in part through interaction with arrestins, whose binding promotes receptor internalization and signaling through G protein-independent pathways. High-affinity arrestin binding requires receptor phosphorylation, often at the receptor’s C-...

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Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Zhou, X. Edward, He, Yuanzheng, de Waal, Parker W., Gao, Xiang, Kang, Yanyong, Van Eps, Ned, Yin, Yanting, Pal, Kuntal, Goswami, Devrishi, White, Thomas A., Barty, Anton, Latorraca, Naomi R., Chapman, Henry N., Hubbell, Wayne L., Dror, Ron O., Stevens, Raymond C., Cherezov, Vadim, Gurevich, Vsevolod V., Griffin, Patrick R., Ernst, Oliver P., Melcher, Karsten, Xu, H. Eric
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567868/
https://ncbi.nlm.nih.gov/pubmed/28753425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.002
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