Identification of Phosphorylation Codes for Arrestin Recruitment by G protein-Coupled Receptors

G protein-coupled receptors (GPCRs) mediate diverse signaling in part through interaction with arrestins, whose binding promotes receptor internalization and signaling through G protein-independent pathways. High-affinity arrestin binding requires receptor phosphorylation, often at the receptor’s C-...

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Publicado no:Cell
Main Authors: Zhou, X. Edward, He, Yuanzheng, de Waal, Parker W., Gao, Xiang, Kang, Yanyong, Van Eps, Ned, Yin, Yanting, Pal, Kuntal, Goswami, Devrishi, White, Thomas A., Barty, Anton, Latorraca, Naomi R., Chapman, Henry N., Hubbell, Wayne L., Dror, Ron O., Stevens, Raymond C., Cherezov, Vadim, Gurevich, Vsevolod V., Griffin, Patrick R., Ernst, Oliver P., Melcher, Karsten, Xu, H. Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567868/
https://ncbi.nlm.nih.gov/pubmed/28753425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.002
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