Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex

Cannabis elicits its mood-enhancing and analgesic effects through the cannabinoid receptor 1 (CB1), a G protein coupled receptor (GPCR) that signals primarily through the adenylyl cyclase-inhibiting heterotrimeric G protein G(i). Activation of CB1-G(i) signaling pathways holds potential for treating...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Cell
Autores principales: Kumar, Kaavya Krishna, Shalev-Benami, Moran, Robertson, Michael J., Hu, Hongli, Banister, Samuel D., Hollingsworth, Scott A., Latorraca, Naomi R., Kato, Hideaki E., Hilger, Daniel, Maeda, Shoji, Weis, William I., Farrens, David L., Dror, Ron O., Malhotra, Sanjay V., Kobilka, Brian K., Skiniotis, Georgios
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461403/
https://ncbi.nlm.nih.gov/pubmed/30639101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.11.040
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares