Id2 and Id3 Define the Potency of Cell Proliferation and Differentiation Responses to Transforming Growth Factor β and Bone Morphogenetic Protein

Por Kowanetz, Marcin, Valcourt, Ulrich, Bergström, Rosita, Heldin, Carl-Henrik, Moustakas, Aristidis
Publicado em 2004

TGF-β and the Smad Signaling Pathway Support Transcriptomic Reprogramming during Epithelial-Mesenchymal Cell Transition

Por Valcourt, Ulrich, Kowanetz, Marcin, Niimi, Hideki, Heldin, Carl-Henrik, Moustakas, Aristidis
Publicado em 2005

TGFβ induces SIK to negatively regulate type I receptor kinase signaling

Por Kowanetz, Marcin, Lönn, Peter, Vanlandewijck, Michael, Kowanetz, Katarzyna, Heldin, Carl-Henrik, Moustakas, Aristidis
Publicado em 2008

The Mechanism of Nuclear Export of Smad3 Involves Exportin 4 and Ran

Por Kurisaki, Akira, Kurisaki, Keiko, Kowanetz, Marcin, Sugino, Hiromu, Yoneda, Yoshihiro, Heldin, Carl-Henrik, Moustakas, Aristidis
Publicado em 2006

MAP kinase inhibitors stimulate T cell and anti-tumor activity in combination with blockade of the PD-L1/PD-1 interaction

Por Irving, Bryan A, Cheung, Jeanne, Yang, Yagai, Moskalenka, Marina, Kowanetz, Marcin, Maecker, Heather, Mellman, Ira
Publicado em 2013

G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models

Por Shojaei, Farbod, Wu, Xiumin, Qu, Xueping, Kowanetz, Marcin, Yu, Lanlan, Tan, Martha, Meng, Y. Gloria, Ferrara, Napoleone
Publicado em 2009

Transcriptional Induction of Salt-inducible Kinase 1 by Transforming Growth Factor β Leads to Negative Regulation of Type I Receptor Signaling in Cooperation with the Smurf2 Ubiqui...

Por Lönn, Peter, Vanlandewijck, Michael, Raja, Erna, Kowanetz, Marcin, Watanabe, Yukihide, Kowanetz, Katarzyna, Vasilaki, Eleftheria, Heldin, Carl-Henrik, Moustakas, Aristidis
Publicado em 2012

A CD4/Foxp3/OX40 triple immunofluorescence assay determines association between T cell immune subsets and outcome in colorectal cancer

Por Ziai, James, Huseni, Mahrukh, Foreman, Oded, Eastham-Anderson, Jeffrey, Xiao, Yuanyuan, Chu, Felix, Kowanetz, Marcin, Hegde, Priti S, Kim, Jeong
Publicado no J Immunother Cancer (2014)

Prevalence analysis of OX40-positive cell populations in solid tumors

Por Ziai, James, Frantz, Gretchen, Zhang, Liping, Kozlowski, Cleopatra, Gilbert, Houston, Smith, Jacquelyn, Kowanetz, Marcin, Kim, Jeong M, Huseni, Mahrukh
Publicado no J Immunother Cancer (2015)

CIN85 Associates with Multiple Effectors Controlling Intracellular Trafficking of Epidermal Growth Factor Receptors

Por Kowanetz, Katarzyna, Husnjak, Koraljka, Höller, Daniela, Kowanetz, Marcin, Soubeyran, Philippe, Hirsch, Dianne, Schmidt, Mirko H.H, Pavelic, Kresimir, De Camilli, Pietro, Randazzo, Paul A., Dikic, Ivan
Publicado em 2004

Intratumoral characteristics of tumor and immune cells at baseline and on-treatment correlated with clinical responses to MPDL3280A, an engineered antibody against PD-L1

Por Kohrt, Holbrook, Kowanetz, Marcin, Gettinger, Scott, Powderly, John, Koeppen, Hartmut, Sosman, Jeffrey A, Cruz, Cristina, Xiao, Yuanyuan, Mokatrin, Ahmad, Fine, Gregg, Chen, Daniel S, Hodi, F Stephen
Publicado em 2013

Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF–induced neutrophil recruitment

Por Phan, Vernon T., Wu, Xiumin, Cheng, Jason H., Sheng, Rebecca X., Chung, Alicia S., Zhuang, Guanglei, Tran, Christopher, Song, Qinghua, Kowanetz, Marcin, Sambrone, Amy, Tan, Martha, Meng, Y. Gloria, Jackson, Erica L., Peale, Franklin V., Junttila, Melissa R., Ferrara, Napoleone
Publicado em 2013

Myeloid cell biology and inhibition of anti-tumor immune responses by MPDL3280A in urothelial bladder cancer

Por Xiao, Yuanyuan, Rabe, Christina, Kowanetz, Marcin, Powles, Thomas, Vogelzang, Nicholas J, Petrylak, Daniel P, Loriot, Yohann, Denker, Mitchell, Nakamura, Rin, Wu, Qun J, Sumiyoshi, Teiko, Boyd, Zachary, Teng, Siew-leng M, Shen, Xiaodong, Fine, Gregg, Chen, Daniel S, Hegde, Priti S
Publicado no J Immunother Cancer (2014)

Immune biomarkers associated with clinical benefit from atezolizumab (MPDL3280a; anti-PD-L1) in advanced urothelial bladder cancer (UBC)

Por Powles, Thomas, Nickles, Dorothee, Van Allen, Eliezer, Chappey, Colombe, Zou, Wei, Kowanetz, Marcin, Kadel, Edward, Denker, Mitchell, Boyd, Zachary, Vogelzang, Nicholas, Kim, Joseph, Bellmunt, Joaquim, Loriot, Yohann, Drake, Charles G, O'Hear, Carol, Fasso, Marcella, Hegde, Priti, Mariathasan, Sanjeev
Publicado no J Immunother Cancer (2015)

Development of a robust flow cytometry-based pharmacodynamic assay to detect phospho-protein signals for phosphatidylinositol 3-kinase inhibitors in multiple myeloma

Por Li, Congfen, Takahashi, Chikara, Zhang, Liangxuan, Huseni, Mahrukh, Stankovich, Basha, Mashhedi, Haider, Lee, Joanna, French, Dorothy, Anderson, Jeff Eastham, Kim, Doris, Howell, Kathy, Brauer, Matthew J, Kowanetz, Marcin, Yan, Yibing, Humke, Eric, Ebens, Allen, Hampton, Garret, Lackner, Mark R, Hegde, Priti, Jia, Shidong
Publicado em 2013

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

Por Kowanetz, Marcin, Wu, Xiumin, Lee, John, Tan, Martha, Hagenbeek, Thijs, Qu, Xueping, Yu, Lanlan, Ross, Jed, Korsisaari, Nina, Cao, Tim, Bou-Reslan, Hani, Kallop, Dara, Weimer, Robby, Ludlam, Mary J. C., Kaminker, Joshua S., Modrusan, Zora, van Bruggen, Nicholas, Peale, Franklin V., Carano, Richard, Meng, Y. Gloria, Ferrara, Napoleone
Publicado em 2010

Circulating and tumor-based biomarkers predict clinical activity in cancer patients treated with the engineered anti-PD-L1 antibody MPDL3280A

Por Kowanetz, Marcin, Rabe, Christina, Xiao, Yuanyuan, Wu, Qun J, Koeppen, Hartmut, Leddy, Cecilia, Patel, Rajesh D, Powderly, John, Kohrt, Holbrook, Gettinger, Scott, Soria, Jean-Charles, Herbst, Roy S, Desai, Rupal, Denker, Mitchell, Ruppel, Jane, Boe, Marigold, Nakamura, Rin, Fu, Ling, Sumiyoshi, Teiko, Mokatrin, Ahmad, Shen, Xiaodong, Fine, Gregg, Chen, Daniel S, Hegde, Priti S
Publicado no J Immunother Cancer (2014)

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

Por Herbst, Roy S., Soria, Jean-Charles, Kowanetz, Marcin, Fine, Gregg D., Hamid, Omid, Gordon, Michael S., Sosman, Jeffery A., McDermott, David F., Powderly, John D., Gettinger, Scott N., Kohrt, Holbrook E. K., Horn, Leora, Lawrence, Donald P., Rost, Sandra, Leabman, Maya, Xiao, Yuanyuan, Mokatrin, Ahmad, Koeppen, Hartmut, Hegde, Priti S., Mellman, Ira, Chen, Daniel S., Hodi, F. Stephen
Publicado no Nature (2014)