Llwytho...

The Mechanism of Nuclear Export of Smad3 Involves Exportin 4 and Ran

Transforming growth factor beta (TGF-β) receptors phosphorylate Smad3 and induce its nuclear import so it can regulate gene transcription. Smad3 can return to the cytoplasm to propagate further cycles of signal transduction or to be degraded. We demonstrate that Smad3 is exported by a constitutive m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kurisaki, Akira, Kurisaki, Keiko, Kowanetz, Marcin, Sugino, Hiromu, Yoneda, Yoshihiro, Heldin, Carl-Henrik, Moustakas, Aristidis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367208/
https://ncbi.nlm.nih.gov/pubmed/16449645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.4.1318-1332.2006
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