TGFβ induces SIK to negatively regulate type I receptor kinase signaling

Signal transduction by transforming growth factor β (TGFβ) coordinates physiological responses in diverse cell types. TGFβ signals via type I and type II receptor serine/threonine kinases and intracellular Smad proteins that regulate transcription. Strength and duration of TGFβ signaling is largely...

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Detalhes bibliográficos
Main Authors: Kowanetz, Marcin, Lönn, Peter, Vanlandewijck, Michael, Kowanetz, Katarzyna, Heldin, Carl-Henrik, Moustakas, Aristidis
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518705/
https://ncbi.nlm.nih.gov/pubmed/18725536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200804107
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