Transcriptional Induction of Salt-inducible Kinase 1 by Transforming Growth Factor β Leads to Negative Regulation of Type I Receptor Signaling in Cooperation with the Smurf2 Ubiquitin Ligase

Transforming growth factor β (TGFβ) regulates many physiological processes and requires control mechanisms to safeguard proper and timely action. We have previously described how negative regulation of TGFβ signaling is controlled by the serine/threonine kinase salt-inducible kinase 1 (SIK1). SIK1 f...

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Main Authors: Lönn, Peter, Vanlandewijck, Michael, Raja, Erna, Kowanetz, Marcin, Watanabe, Yukihide, Kowanetz, Katarzyna, Vasilaki, Eleftheria, Heldin, Carl-Henrik, Moustakas, Aristidis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339966/
https://ncbi.nlm.nih.gov/pubmed/22378783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.307249
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