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Transforming Growth Factor-β Induces Nuclear Import of Smad3 in an Importin-β1 and Ran-dependent Manner

Smad proteins are cytoplasmic signaling effectors of transforming growth factor-β (TGF-β) family cytokines and regulate gene transcription in the nucleus. Receptor-activated Smads (R-Smads) become phosphorylated by the TGF-β type I receptor. Rapid and precise transport of R-Smads to the nucleus is o...

詳細記述

保存先:
書誌詳細
主要な著者: Kurisaki, Akira, Kose, Shingo, Yoneda, Yoshihiro, Heldin, Carl-Henrik, Moustakas, Aristidis
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC32288/
https://ncbi.nlm.nih.gov/pubmed/11294908
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