Transforming Growth Factor-β Induces Nuclear Import of Smad3 in an Importin-β1 and Ran-dependent Manner

Smad proteins are cytoplasmic signaling effectors of transforming growth factor-β (TGF-β) family cytokines and regulate gene transcription in the nucleus. Receptor-activated Smads (R-Smads) become phosphorylated by the TGF-β type I receptor. Rapid and precise transport of R-Smads to the nucleus is o...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Kurisaki, Akira, Kose, Shingo, Yoneda, Yoshihiro, Heldin, Carl-Henrik, Moustakas, Aristidis
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC32288/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11294908/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.4.1079
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