The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein–coupled receptors

by Yan, Yibing, Shirakabe, Kyoko, Werb, Zena
Published 2002

Robust network inference using response logic

by Gross, Torsten, Wongchenko, Matthew J, Yan, Yibing, Blüthgen, Nils
Published in Bioinformatics (2019)

The cancer cell proteome and transcriptome predicts sensitivity to targeted and cytotoxic drugs

by Rydenfelt, Mattias, Wongchenko, Matthew, Klinger, Bertram, Yan, Yibing, Blüthgen, Nils
Published in Life Sci Alliance (2019)

Topological Organization Alterations of Whole-Brain Functional Networks in Patients with Childhood Absence Epilepsy: Associations with Treatment Effects

by Wang, Xueyu, Fang, Peng, Jiao, Dongmei, Hu, Tian, Yang, Qi, Liang, Wei, Li, Yijun, Yan, Yibing, Liu, Libo
Published in Dis Markers (2021)

HSP105 Recruits Protein Phosphatase 2A To Dephosphorylate β-Catenin

by Yu, Nancy, Kakunda, Michael, Pham, Victoria, Lill, Jennie R., Du, Pan, Wongchenko, Matthew, Yan, Yibing, Firestein, Ron, Huang, XiaoDong
Published in Mol Cell Biol (2015)

Biomarker analysis of on-treatment and at progression biopsies from BRIM7 - a phase 1B trial of combined vemurafenib and cobimetinib treatment in BRAF V600 mutated melanoma

by Yan, Yibing, McArthur, Grant, Hamid, Omid, Puzanov, Igor, Gonzalez, Rene, Gajewski, Thomas, Wang, Yulei, Wongchenko, Matthew, Choong, Nicholas, Ribas, Antoni
Published 2014

Improved Cognitive Promotion through Accelerated Magnetic Stimulation

by Wu, Xingqi, Wang, Lu, Geng, Zhi, Wei, Ling, Yan, Yibing, Xie, Chengjuan, Chen, Xingui, Ji, Gong-Jun, Tian, Yanghua, Wang, Kai
Published in eNeuro (2021)

Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice

by Carlson, Timothy R., Yan, Yibing, Wu, Xiaoqing, Lam, Michael T., Tang, Gale L., Beverly, Levi J., Messina, Louis M., Capobianco, Anthony J., Werb, Zena, Wang, Rong
Published 2005

Network quantification of EGFR signaling unveils potential for targeted combination therapy

by Klinger, Bertram, Sieber, Anja, Fritsche-Guenther, Raphaela, Witzel, Franziska, Berry, Leanne, Schumacher, Dirk, Yan, Yibing, Durek, Pawel, Merchant, Mark, Schäfer, Reinhold, Sers, Christine, Blüthgen, Nils
Published 2013

Amphiregulin and PTEN evoke a multimodal mechanism of acquired resistance to PI3K inhibition

by Edgar, Kyle A., Crocker, Lisa, Cheng, Eric, Wagle, Marie-Claire, Wongchenko, Matthew, Yan, Yibing, Wilson, Timothy R., Dompe, Nicholas, Neve, Richard M., Belvin, Marcia, Sampath, Deepak, Friedman, Lori S., Wallin, Jeffrey J.
Published 2014

Impact of depth of response on survival in patients treated with cobimetinib ± vemurafenib: pooled analysis of BRIM-2, BRIM-3, BRIM-7 and coBRIM

by Lewis, Karl D., Larkin, James, Ribas, Antoni, Flaherty, Keith T., McArthur, Grant A., Ascierto, Paolo A., Dréno, Brigitte, Yan, Yibing, Wongchenko, Matthew, McKenna, Edward, Zhu, Qian, Mun, Yong, Hauschild, Axel
Published in Br J Cancer (2019)

Extended 5-Year Follow-Up Results of a Phase 1b Study (BRIM7) of Vemurafenib and Cobimetinib in BRAF-Mutant Melanoma

by Ribas, Antoni, Daud, Adil, Pavlick, Anna C., Gonzalez, Rene, Lewis, Karl D., Hamid, Omid, Gajewski, Thomas F., Puzanov, Igor, Wongchenko, Matthew, Rooney, Isabelle, Hsu, Jessie J., Yan, Yibing, Park, Erica, McArthur, Grant A.
Published in Clin Cancer Res (2019)

Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors

by Wilson, Timothy R., Fridlyand, Jane, Yan, Yibing, Penuel, Elicia, Burton, Luciana, Chan, Emily, Peng, Jing, Lin, Eva, Wang, Yulei, Sosman, Jeff, Ribas, Antoni, Li, Jiang, Moffat, John, Sutherlin, Daniel P., Koeppen, Hartmut, Merchant, Mark, Neve, Richard, Settleman, Jeff
Published 2012

Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation

by Long, Jason E., Wongchenko, Matthew J., Nickles, Dorothee, Chung, Wei-Jen, Wang, Bu-er, Riegler, Johannes, Li, Ji, Li, Qingling, Sandoval, Wendy, Eastham-Anderson, Jeff, Modrusan, Zora, Junttila, Teemu, Carano, Richard A. D., Foreman, Oded, Yan, Yibing, Junttila, Melissa R.
Published in Cell Death Differ (2019)

Critical role for Syk in responses to vascular injury

by Andre, Patrick, Morooka, Toshifumi, Sim, Derek, Abe, Keith, Lowell, Clifford, Nanda, Nisha, Delaney, Suzanne, Siu, Gail, Yan, Yibing, Hollenbach, Stan, Pandey, Anjali, Gao, Huiyun, Wang, Yunmei, Nakajima, Kohsuke, Parikh, Sahil A., Shi, Can, Phillips, David, Owen, Whyte, Sinha, Uma, Simon, Daniel I.
Published 2011

Development of a robust flow cytometry-based pharmacodynamic assay to detect phospho-protein signals for phosphatidylinositol 3-kinase inhibitors in multiple myeloma

by Li, Congfen, Takahashi, Chikara, Zhang, Liangxuan, Huseni, Mahrukh, Stankovich, Basha, Mashhedi, Haider, Lee, Joanna, French, Dorothy, Anderson, Jeff Eastham, Kim, Doris, Howell, Kathy, Brauer, Matthew J, Kowanetz, Marcin, Yan, Yibing, Humke, Eric, Ebens, Allen, Hampton, Garret, Lackner, Mark R, Hegde, Priti, Jia, Shidong
Published 2013

Genomic features of exceptional response in vemurafenib ± cobimetinib–treated patients with BRAF(V600)-mutated metastatic melanoma

by Yan, Yibing, Wongchenko, Matthew J., Robert, Caroline, Larkin, James, Ascierto, Paolo A., Dréno, Brigitte, Maio, Michele, Garbe, Claus, Chapman, Paul B., Sosman, Jeffrey A., Shi, Zhen, Koeppen, Hartmut, Hsu, Jessie J., Chang, Ilsung, Caro, Ivor, Rooney, Isabelle, McArthur, Grant A., Ribas, Antoni
Published in Clin Cancer Res (2019)

A First-in-Human Phase I Study of the ATP-Competitive AKT Inhibitor Ipatasertib Demonstrates Robust and Safe Targeting of AKT in Patients with Solid Tumors

by Saura, Cristina, Roda, Desamparados, Roselló, Susana, Oliveira, Mafalda, Macarulla, Teresa, Pérez-Fidalgo, José Alejandro, Morales-Barrera, Rafael, Sanchis-García, Juan Manuel, Musib, Luna, Budha, Nageshwar, Zhu, Jin, Nannini, Michelle, Chan, Wai Y., Sanabria Bohórquez, Sandra M., Meng, Raymond D., Lin, Kui, Yan, Yibing, Patel, Premal, Baselga, José, Tabernero, Josep, Cervantes, Andrés
Published in Cancer Discov (2016)

Distinct molecular profiles and immunotherapy treatment outcomes of V600E and V600K BRAF-mutant melanoma

by da Silva, Inês Pires, Wang, Kevin YX, Wilmott, James S, Holst, Jeff, Carlino, Matteo S, Park, John J, Quek, Camelia, Wongchenko, Matthew, Yan, Yibing, Mann, Graham, Johnson, Douglas B., McQuade, Jennifer L, Rai, Rajat, Kefford, Richard F, Rizos, Helen, Scolyer, Richard A, Yang, Jean YU, Long, Georgina V, Menzies, Alexander M
Published in Clin Cancer Res (2019)

First-in-human Phase I study of Pictilisib (GDC-0941), a potent pan-class I phosphatidylinositol-3-kinase (PI3K) inhibitor, in patients with advanced solid tumors

by Sarker, Debashis, Ang, Joo Ern, Baird, Richard, Kristeleit, Rebecca, Shah, Krunal, Moreno, Victor, Clarke, Paul A., Raynaud, Florence I., Levy, Gallia, Ware, Joseph A, Mazina, Kathryn, Lin, Ray, Wu, Jenny, Fredrickson, Jill, Spoerke, Jill M, Lackner, Mark R, Yan, Yibing, Friedman, Lori S., Kaye, Stan B., Derynck, Mika K., Workman, Paul, de Bono, Johann S.
Published in Clin Cancer Res (2014)