Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

Priming of the organ-specific premetastatic sites is thought to be an important yet incompletely understood step during metastasis. In this study, we show that the metastatic tumors we examined overexpress granulocyte-colony stimulating factor (G-CSF), which expands and mobilizes Ly6G+Ly6C+ granuloc...

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Detalhes bibliográficos
Main Authors: Kowanetz, Marcin, Wu, Xiumin, Lee, John, Tan, Martha, Hagenbeek, Thijs, Qu, Xueping, Yu, Lanlan, Ross, Jed, Korsisaari, Nina, Cao, Tim, Bou-Reslan, Hani, Kallop, Dara, Weimer, Robby, Ludlam, Mary J. C., Kaminker, Joshua S., Modrusan, Zora, van Bruggen, Nicholas, Peale, Franklin V., Carano, Richard, Meng, Y. Gloria, Ferrara, Napoleone
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003076/
https://ncbi.nlm.nih.gov/pubmed/21081700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015855107
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