Biochemical Similarities between Soluble and Membrane-Bound Calcium-Dependent Protein Kinases of Barley

por Klimczak, Leszek J., Hind, Geoffrey
Publicado 1990

Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic

por Klimczak, Leszek J., Randall, Thomas A., Saini, Natalie, Li, Jian-Liang, Gordenin, Dmitry A.
Publicado en bioRxiv (2020)

Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic

por Klimczak, Leszek J., Randall, Thomas A., Saini, Natalie, Li, Jian-Liang, Gordenin, Dmitry A.
Publicado en PLoS One (2020)

Mixture Analyses of Air-sampled Pollen Extracts Can Accurately Differentiate Pollen Taxa

por Klimczak, Leszek J., von Eschenbach, Cordula Ebner, Thompson, Peter M., Buters, Jeroen T.M., Mueller, Geoffrey A.
Publicado en Atmos Environ (1994) (2020)

APOBEC-induced cancer mutations are uniquely enriched in early replicating, gene dense, and active chromatin regions

por Kazanov, Marat D., Roberts, Steven A., Polak, Paz, Stamatoyannopoulos, John, Klimczak, Leszek J., Gordenin, Dmitry A., Sunyaev, Shamil R.
Publicado en Cell Rep (2015)

Mutational signatures of redox stress in yeast single-strand DNA and of aging in human mitochondrial DNA share a common feature

por Degtyareva, Natalya P., Saini, Natalie, Sterling, Joan F., Placentra, Victoria C., Klimczak, Leszek J., Gordenin, Dmitry A., Doetsch, Paul W.
Publicado en PLoS Biol (2019)

Detection of genome-wide polymorphisms in the AT-rich Plasmodium falciparum genome using a high-density microarray

por Jiang, Hongying, Yi, Ming, Mu, Jianbing, Zhang, Louie, Ivens, Al, Klimczak, Leszek J, Huyen, Yentram, Stephens, Robert M, Su, Xin-zhuan
Publicado 2008

APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis

por Maciejowski, John, Chatzipli, Aikaterini, Dananberg, Alexandra, Chu, Kevan, Toufektchan, Eleonore, Klimczak, Leszek J., Gordenin, Dmitry A., Campbell, Peter J., de Lange, Titia
Publicado en Nat Genet (2020)

Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases

por Sui, Yang, Qi, Lei, Zhang, Ke, Saini, Natalie, Klimczak, Leszek J., Sakofsky, Cynthia J., Gordenin, Dmitry A., Petes, Thomas D., Zheng, Dao-Qiong
Publicado en Proc Natl Acad Sci U S A (2020)

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

por Sakofsky, Cynthia J., Saini, Natalie, Klimczak, Leszek J., Chan, Kin, Malc, Ewa P., Mieczkowski, Piotr A., Burkholder, Adam B., Fargo, David, Gordenin, Dmitry A.
Publicado en PLoS Biol (2019)

Correction: Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

por Sakofsky, Cynthia J., Saini, Natalie, Klimczak, Leszek J., Chan, Kin, Malc, Ewa P., Mieczkowski, Piotr A., Burkholder, Adam B., Fargo, David, Gordenin, Dmitry A.
Publicado en PLoS Biol (2020)

Mutation signatures specific to DNA alkylating agents in yeast and cancers

por Saini, Natalie, Sterling, Joan F, Sakofsky, Cynthia J, Giacobone, Camille K, Klimczak, Leszek J, Burkholder, Adam B, Malc, Ewa P, Mieczkowski, Piotr A, Gordenin, Dmitry A
Publicado en Nucleic Acids Res (2020)

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

por Cortés-Ciriano, Isidro, Lee, Jake June-Koo, Xi, Ruibin, Jain, Dhawal, Jung, Youngsook L., Yang, Lixing, Gordenin, Dmitry, Klimczak, Leszek J., Zhang, Cheng-Zhong, Pellman, David S., Park, Peter J.
Publicado en Nat Genet (2020)

Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions

por Roberts, Steven A., Sterling, Joan, Thompson, Cole, Harris, Shawn, Mav, Deepak, Shah, Ruchir, Klimczak, Leszek J., Kryukov, Gregory V., Malc, Ewa, Mieczkowski, Piotr A., Resnick, Michael A., Gordenin, Dmitry A.
Publicado 2012

An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers

por Chan, Kin, Roberts, Steven A., Klimczak, Leszek J., Sterling, Joan F., Saini, Natalie, Malc, Ewa P., Kim, Jaegil, Kwiatkowski, David J., Fargo, David C., Mieczkowski, Piotr A., Getz, Gad, Gordenin, Dmitry A.
Publicado en Nat Genet (2015)

UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin

por Saini, Natalie, Giacobone, Camille K., Klimczak, Leszek J., Papas, Brian N., Burkholder, Adam B., Li, Jian-Liang, Fargo, David C., Bai, Re, Gerrish, Kevin, Innes, Cynthia L., Schurman, Shepherd H., Gordenin, Dmitry A.
Publicado en PLoS Genet (2021)

An APOBEC Cytidine Deaminase Mutagenesis Pattern is Widespread in Human Cancers

por Roberts, Steven A., Lawrence, Michael S., Klimczak, Leszek J., Grimm, Sara A., Fargo, David, Stojanov, Petar, Kiezun, Adam, Kryukov, Gregory V., Carter, Scott L., Saksena, Gordon, Harris, Shawn, Shah, Ruchir R., Resnick, Michael A., Getz, Gad, Gordenin, Dmitry A.
Publicado 2013

Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies

por Perelygina, Ludmila, Chen, Min-hsin, Suppiah, Suganthi, Adebayo, Adebola, Abernathy, Emily, Dorsey, Morna, Bercovitch, Lionel, Paris, Kenneth, White, Kevin P., Krol, Alfons, Dhossche, Julie, Torshin, Ivan Y., Saini, Natalie, Klimczak, Leszek J., Gordenin, Dmitry A., Zharkikh, Andrey, Plotkin, Stanley, Sullivan, Kathleen E., Icenogle, Joseph
Publicado en PLoS Pathog (2019)

The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts

por Saini, Natalie, Roberts, Steven A., Klimczak, Leszek J., Chan, Kin, Grimm, Sara A., Dai, Shuangshuang, Fargo, David C., Boyer, Jayne C., Kaufmann, William K., Taylor, Jack A., Lee, Eunjung, Cortes-Ciriano, Isidro, Park, Peter J., Schurman, Shepherd H., Malc, Ewa P., Mieczkowski, Piotr A., Gordenin, Dmitry A.
Publicado en PLoS Genet (2016)

Genomic Subtypes of Non-Invasive Bladder Cancer with Distinct Metabolic Profile, Clinical Outcome and Female Gender Bias in KDM6A Mutation Frequency

por Hurst, Carolyn D., Alder, Olivia, Platt, Fiona M., Droop, Alastair, Stead, Lucy F., Burns, Julie E., Burghel, George J., Jain, Sunjay, Klimczak, Leszek J., Lindsay, Helen, Roulson, Jo-An, Taylor, Claire F., Thygesen, Helene, Cameron, Angus J., Ridley, Anne J., Mott, Helen R., Gordenin, Dmitry A., Knowles, Margaret A.
Publicado en Cancer Cell (2017)