Phosphatidylinositol 3-kinase (PI3K) pathway activation in bladder cancer

Por Knowles, Margaret A., Platt, Fiona M., Ross, Rebecca L., Hurst, Carolyn D.
Publicado em 2009

Novel Tumor Subgroups of Urothelial Carcinoma of the Bladder Defined by Integrated Genomic Analysis

Por Hurst, Carolyn D., Platt, Fiona M., Taylor, Claire F., Knowles, Margaret A.
Publicado no Clin Cancer Res (2012)

Bladder tumour-derived somatic TSC1 missense mutations cause loss of function via distinct mechanisms

Por Pymar, Louis S., Platt, Fiona M., Askham, Jon M., Morrison, Ewan E., Knowles, Margaret A.
Publicado em 2008

Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification

Por Hurst, Carolyn D., Tomlinson, Darren C., Williams, Sarah V., Platt, Fiona M., Knowles, Margaret A.
Publicado em 2007

Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes

Por Taylor, Claire F., Platt, Fiona M., Hurst, Carolyn D., Thygesen, Helene H., Knowles, Margaret A.
Publicado em 2014

Genomic Subtypes of Non-Invasive Bladder Cancer with Distinct Metabolic Profile, Clinical Outcome and Female Gender Bias in KDM6A Mutation Frequency

Por Hurst, Carolyn D., Alder, Olivia, Platt, Fiona M., Droop, Alastair, Stead, Lucy F., Burns, Julie E., Burghel, George J., Jain, Sunjay, Klimczak, Leszek J., Lindsay, Helen, Roulson, Jo-An, Taylor, Claire F., Thygesen, Helene, Cameron, Angus J., Ridley, Anne J., Mott, Helen R., Gordenin, Dmitry A., Knowles, Margaret A.
Publicado no Cancer Cell (2017)