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Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases

Yeast strains with low levels of the replicative DNA polymerases (alpha, delta, and epsilon) have high levels of chromosome deletions, duplications, and translocations. By examining the patterns of mutations induced in strains with low levels of DNA polymerase by the human protein APOBEC3B (a protei...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Sui, Yang, Qi, Lei, Zhang, Ke, Saini, Natalie, Klimczak, Leszek J., Sakofsky, Cynthia J., Gordenin, Dmitry A., Petes, Thomas D., Zheng, Dao-Qiong
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196835/
https://ncbi.nlm.nih.gov/pubmed/32277034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922472117
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