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Genome Instability Induced by Low Levels of Replicative DNA Polymerases in Yeast

Most cells of solid tumors have very high levels of genome instability of several different types, including deletions, duplications, translocations, and aneuploidy. Much of this instability appears induced by DNA replication stress. As a model for understanding this type of instability, we have exa...

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Vydáno v:Genes (Basel)
Hlavní autoři: Zheng, Dao-Qiong, Petes, Thomas D.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267110/
https://ncbi.nlm.nih.gov/pubmed/30405078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9110539
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