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Global analysis of genomic instability caused by DNA replication stress in Saccharomyces cerevisiae
DNA replication stress (DRS)-induced genomic instability is an important factor driving cancer development. To understand the mechanisms of DRS-associated genomic instability, we measured the rates of genomic alterations throughout the genome in a yeast strain with lowered expression of the replicat...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5167146/ https://ncbi.nlm.nih.gov/pubmed/27911848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618129113 |
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