Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases

Yeast strains with low levels of the replicative DNA polymerases (alpha, delta, and epsilon) have high levels of chromosome deletions, duplications, and translocations. By examining the patterns of mutations induced in strains with low levels of DNA polymerase by the human protein APOBEC3B (a protei...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Sui, Yang, Qi, Lei, Zhang, Ke, Saini, Natalie, Klimczak, Leszek J., Sakofsky, Cynthia J., Gordenin, Dmitry A., Petes, Thomas D., Zheng, Dao-Qiong
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196835/
https://ncbi.nlm.nih.gov/pubmed/32277034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922472117
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