An APOBEC Cytidine Deaminase Mutagenesis Pattern is Widespread in Human Cancers

Recent studies indicate that a subclass of APOBEC cytidine deaminases, which convert cytosine to uracil during RNA editing and retrovirus or retrotransposon restriction, may induce mutation clusters in human tumors. We show here that throughout cancer genomes APOBEC mutagenesis is pervasive and corr...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Roberts, Steven A., Lawrence, Michael S., Klimczak, Leszek J., Grimm, Sara A., Fargo, David, Stojanov, Petar, Kiezun, Adam, Kryukov, Gregory V., Carter, Scott L., Saksena, Gordon, Harris, Shawn, Shah, Ruchir R., Resnick, Michael A., Getz, Gad, Gordenin, Dmitry A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789062/
https://ncbi.nlm.nih.gov/pubmed/23852170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2702
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars