Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies

Rubella viruses (RV) have been found in an association with granulomas in children with primary immune deficiencies (PID). Here, we report the recovery and characterization of infectious immunodeficiency-related vaccine-derived rubella viruses (iVDRV) from diagnostic skin biopsies of four patients....

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Perelygina, Ludmila, Chen, Min-hsin, Suppiah, Suganthi, Adebayo, Adebola, Abernathy, Emily, Dorsey, Morna, Bercovitch, Lionel, Paris, Kenneth, White, Kevin P., Krol, Alfons, Dhossche, Julie, Torshin, Ivan Y., Saini, Natalie, Klimczak, Leszek J., Gordenin, Dmitry A., Zharkikh, Andrey, Plotkin, Stanley, Sullivan, Kathleen E., Icenogle, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6837625/
https://ncbi.nlm.nih.gov/pubmed/31658304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008080
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