Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies

Rubella viruses (RV) have been found in an association with granulomas in children with primary immune deficiencies (PID). Here, we report the recovery and characterization of infectious immunodeficiency-related vaccine-derived rubella viruses (iVDRV) from diagnostic skin biopsies of four patients....

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Udgivet i:PLoS Pathog
Main Authors: Perelygina, Ludmila, Chen, Min-hsin, Suppiah, Suganthi, Adebayo, Adebola, Abernathy, Emily, Dorsey, Morna, Bercovitch, Lionel, Paris, Kenneth, White, Kevin P., Krol, Alfons, Dhossche, Julie, Torshin, Ivan Y., Saini, Natalie, Klimczak, Leszek J., Gordenin, Dmitry A., Zharkikh, Andrey, Plotkin, Stanley, Sullivan, Kathleen E., Icenogle, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6837625/
https://ncbi.nlm.nih.gov/pubmed/31658304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008080
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