ENaC structure and function in the wake of a resolved structure of a family member

door Kashlan, Ossama B., Kleyman, Thomas R.
Gepubliceerd in 2011

Epithelial Na(+) Channel Regulation by Cytoplasmic and Extracellular Factors

door Kashlan, Ossama B., Kleyman, Thomas R.
Gepubliceerd in 2012

Rational polynomial representation of ribonucleotide reductase activity

door Radivoyevitch, Tomas, Kashlan, Ossama B, Cooperman, Barry S
Gepubliceerd in 2005

Epithelial Na(+) Channel Regulation by Extracellular and Intracellular Factors

door Kleyman, Thomas R., Kashlan, Ossama B., Hughey, Rebecca P.
Gepubliceerd in Annu Rev Physiol (2017)

Conserved cysteines in the finger domain of the epithelial Na(+) channel α and γ subunits are proximal to the dynamic finger–thumb domain interface

door Blobner, Brandon M., Wang, Xue-Ping, Kashlan, Ossama B.
Gepubliceerd in J Biol Chem (2018)

The epithelial Na(+) channel γ subunit autoinhibitory tract suppresses channel activity by binding the γ subunit's finger–thumb domain interface

door Balchak, Deidra M., Thompson, Rebecca N., Kashlan, Ossama B.
Gepubliceerd in J Biol Chem (2018)

Insights into the Mechanism of Pore Opening of Acid-sensing Ion Channel 1A

door Tolino, Lindsey A., Okumura, Sora, Kashlan, Ossama B., Carattino, Marcelo D.
Gepubliceerd in 2011

Extracellular Finger Domain Modulates the Response of the Epithelial Sodium Channel to Shear Stress

door Shi, Shujie, Blobner, Brandon M., Kashlan, Ossama B., Kleyman, Thomas R.
Gepubliceerd in 2012

Na(+) Inhibits the Epithelial Na(+) Channel by Binding to a Site in an Extracellular Acidic Cleft

door Kashlan, Ossama B., Blobner, Brandon M., Zuzek, Zachary, Tolino, Michael, Kleyman, Thomas R.
Gepubliceerd in J Biol Chem (2015)

Inhibitory Tract Traps the Epithelial Na(+) Channel in a Low Activity Conformation

door Kashlan, Ossama B., Blobner, Brandon M., Zuzek, Zachary, Carattino, Marcelo D., Kleyman, Thomas R.
Gepubliceerd in 2012

Pore-lining residues of MEC-4 and MEC-10 channel subunits tune the Caenorhabditis elegans degenerin channel's response to shear stress

door Shi, Shujie, Mutchler, Stephanie M., Blobner, Brandon M., Kashlan, Ossama B., Kleyman, Thomas R.
Gepubliceerd in J Biol Chem (2018)

Collecting Duct Principal Cell Transport Processes and Their Regulation

door Pearce, David, Soundararajan, Rama, Trimpert, Christiane, Kashlan, Ossama B., Deen, Peter M.T., Kohan, Donald E.
Gepubliceerd in Clin J Am Soc Nephrol (2015)

Allosteric Inhibition of the Epithelial Na(+) Channel through Peptide Binding at Peripheral Finger and Thumb Domains

door Kashlan, Ossama B., Boyd, Cary R., Argyropoulos, Christos, Okumura, Sora, Hughey, Rebecca P., Grabe, Michael, Kleyman, Thomas R.
Gepubliceerd in 2010

Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel

door Passero, Christopher J., Carattino, Marcelo D., Kashlan, Ossama B., Myerburg, Mike M., Hughey, Rebecca P., Kleyman, Thomas R.
Gepubliceerd in 2010

Base of the Thumb Domain Modulates Epithelial Sodium Channel Gating

door Shi, Shujie, Ghosh, D. Dipon, Okumura, Sora, Carattino, Marcelo D., Kashlan, Ossama B., Sheng, Shaohu, Kleyman, Thomas R.
Gepubliceerd in 2011

Differential effects of Hsc70 and Hsp70 on the intracellular trafficking and functional expression of epithelial sodium channels

door Goldfarb, Samuel B., Kashlan, Ossama B., Watkins, Jeffrey N., Suaud, Laurence, Yan, Wusheng, Kleyman, Thomas R., Rubenstein, Ronald C.
Gepubliceerd in 2006

Multiple motifs regulate apical sorting of p75 via a mechanism that involves dimerization and higher-order oligomerization

door Youker, Robert T., Bruns, Jennifer R., Costa, Simone A., Rbaibi, Youssef, Lanni, Frederick, Kashlan, Ossama B., Teng, Haibing, Weisz, Ora A.
Gepubliceerd in 2013

Murine epithelial sodium (Na(+)) channel regulation by biliary factors

door Wang, Xue-Ping, Im, Seohyun Janice, Balchak, Deidra M., Montalbetti, Nicolas, Carattino, Marcelo D., Ray, Evan C., Kashlan, Ossama B.
Gepubliceerd in J Biol Chem (2019)

Constraint-based, Homology Model of the Extracellular Domain of the Epithelial Na(+) Channel α Subunit Reveals a Mechanism of Channel Activation by Proteases

door Kashlan, Ossama B., Adelman, Joshua L., Okumura, Sora, Blobner, Brandon M., Zuzek, Zachary, Hughey, Rebecca P., Kleyman, Thomas R., Grabe, Michael
Gepubliceerd in 2011

Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine

door Pan, Jianjun, Chen, Qiang, Willenbring, Dan, Yoshida, Ken, Tillman, Tommy, Kashlan, Ossama B., Cohen, Aina, Kong, Xiang-Peng, Xu, Yan, Tang, Pei
Gepubliceerd in 2012