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Conserved cysteines in the finger domain of the epithelial Na(+) channel α and γ subunits are proximal to the dynamic finger–thumb domain interface

The epithelial Na(+) channel (ENaC) is a member of the ENaC/degenerin family of ion channels. In the structure of a related family member, the “thumb” domain's base interacts with the pore, and its tip interacts with the divergent “finger” domain. Between the base and tip, the thumb domain is c...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Blobner, Brandon M., Wang, Xue-Ping, Kashlan, Ossama B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880152/
https://ncbi.nlm.nih.gov/pubmed/29425099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.819367
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