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Extracellular Finger Domain Modulates the Response of the Epithelial Sodium Channel to Shear Stress

The epithelial sodium channel (ENaC) is regulated by multiple extracellular stimuli, including shear stress. Previous studies suggest that the extracellular finger domains of ENaC α and γ subunits contain allosteric regulatory modules. However, the role of the finger domain in the shear stress respo...

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Main Authors: Shi, Shujie, Blobner, Brandon M., Kashlan, Ossama B., Kleyman, Thomas R.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346134/
https://ncbi.nlm.nih.gov/pubmed/22408250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.346551
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