Base of the Thumb Domain Modulates Epithelial Sodium Channel Gating

The activity of the epithelial sodium channel (ENaC) is modulated by multiple external factors, including proteases, cations, anions and shear stress. The resolved crystal structure of acid-sensing ion channel 1 (ASIC1), a structurally related ion channel, and mutagenesis studies suggest that the la...

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Detaylı Bibliyografya
Asıl Yazarlar: Shi, Shujie, Ghosh, D. Dipon, Okumura, Sora, Carattino, Marcelo D., Kashlan, Ossama B., Sheng, Shaohu, Kleyman, Thomas R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2011
Konular:
Membrane Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083234/
https://ncbi.nlm.nih.gov/pubmed/21367859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.191734
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