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Novel Determinants of Epithelial Sodium Channel Gating within Extracellular Thumb Domains
Activity of the epithelial Na(+) channel (ENaC) is modulated by Na(+) self-inhibition, an allosteric down-regulation of channel open probability by extracellular Na(+). We searched for determinants of Na(+) self-inhibition by analyzing changes in this inhibitory response resulting from specific muta...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2658069/ https://ncbi.nlm.nih.gov/pubmed/19158091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807060200 |
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