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Conformational Changes Associated with Proton-dependent Gating of ASIC1a
Acid-sensing ion channels are proton-gated Na(+) channels expressed predominantly in neurons. How channel structure translates an environmental stimulus into changes in pore permeability remains largely undefined. The pore of ASIC1 is defined by residues in the second transmembrane domain (TM2), alt...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794763/ https://ncbi.nlm.nih.gov/pubmed/19858190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.055418 |
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