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Independent Contribution of Extracellular Proton Binding Sites to ASIC1a Activation
Acid-sensing ion channels (ASICs) are a group of trimeric cation permeable channels gated by extracellular protons that are mainly expressed in the nervous system. Despite the structural information available for ASIC1, there is limited understanding of the molecular mechanism that allows these chan...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3843052/ https://ncbi.nlm.nih.gov/pubmed/24142696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.504324 |
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