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Independent Contribution of Extracellular Proton Binding Sites to ASIC1a Activation

Acid-sensing ion channels (ASICs) are a group of trimeric cation permeable channels gated by extracellular protons that are mainly expressed in the nervous system. Despite the structural information available for ASIC1, there is limited understanding of the molecular mechanism that allows these chan...

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Detalles Bibliográficos
Main Authors: Krauson, Aram J., Rued, Anna C., Carattino, Marcelo D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843052/
https://ncbi.nlm.nih.gov/pubmed/24142696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.504324
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