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Base of the Thumb Domain Modulates Epithelial Sodium Channel Gating
The activity of the epithelial sodium channel (ENaC) is modulated by multiple external factors, including proteases, cations, anions and shear stress. The resolved crystal structure of acid-sensing ion channel 1 (ASIC1), a structurally related ion channel, and mutagenesis studies suggest that the la...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3083234/ https://ncbi.nlm.nih.gov/pubmed/21367859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.191734 |
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