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Second transmembrane domain modulates epithelial sodium channel gating in response to shear stress
Na(+) absorption and K(+) secretion in the distal segments of the nephron are modulated by the tubular flow rate. Epithelial Na(+) channels (ENaC), composed of α-, β-, and γ-subunits respond to laminar shear stress (LSS) with an increase in open probability. Higher vertebrates express a δ-ENaC subun...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3094055/ https://ncbi.nlm.nih.gov/pubmed/21307123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00610.2010 |
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