A disease-associated mutation that weakens ZAP70 autoinhibition enhances responses to weak and self ligands

av Shen, Lin, Matloubian, Mehrdad, Kadlecek, Theresa A., Weiss, Arthur
I publikationen Sci Signal (2021)

Stability of an autoinhibitory interface in the structure of the tyrosine kinase ZAP-70 impacts T cell receptor response

av Deindl, Sebastian, Kadlecek, Theresa A., Cao, Xiaoxian, Kuriyan, John, Weiss, Arthur
Publicerad 2009

Intramolecular Regulatory Switch in ZAP-70: Analogy with Receptor Tyrosine Kinases

av Brdicka, Tomas, Kadlecek, Theresa A., Roose, Jeroen P., Pastuszak, Alexander W., Weiss, Arthur
Publicerad 2005

Inhibition of ZAP-70 Kinase Activity via an Analog-sensitive Allele Blocks T Cell Receptor and CD28 Superagonist Signaling

av Levin, Susan E., Zhang, Chao, Kadlecek, Theresa A., Shokat, Kevan M., Weiss, Arthur
Publicerad 2008

Expression and Function of Tec, Itk, and Btk in Lymphocytes: Evidence for a Unique Role for Tec

av Tomlinson, Michael G., Kane, Lawrence P., Su, Jennifer, Kadlecek, Theresa A., Mollenauer, Marianne N., Weiss, Arthur
Publicerad 2004

Structural Basis for Activation of ZAP-70 by Phosphorylation of the SH2-Kinase Linker

av Yan, Qingrong, Barros, Tiago, Visperas, Patrick R., Deindl, Sebastian, Kadlecek, Theresa A., Weiss, Arthur, Kuriyan, John
Publicerad 2013

Switch-like activation of Bruton’s tyrosine kinase by membrane-mediated dimerization

av Chung, Jean K., Nocka, Laura M., Decker, Aubrianna, Wang, Qi, Kadlecek, Theresa A., Weiss, Arthur, Kuriyan, John, Groves, Jay T.
I publikationen Proc Natl Acad Sci U S A (2019)

ZAP-70: An Essential Kinase in T-cell Signaling

av Wang, Haopeng, Kadlecek, Theresa A., Au-Yeung, Byron B., Goodfellow, Hanna E. Sjölin, Hsu, Lih-Yun, Freedman, Tanya S., Weiss, Arthur
Publicerad 2010

A PHOSPHOSITE WITHIN THE SH2 DOMAIN OF LCK REGULATES ITS ACTIVATION BY CD45

av Courtney, Adam H., Amacher, Jeanine F., Kadlecek, Theresa A., Mollenauer, Marianne N., Au-Yeung, Byron B., Kuriyan, John, Weiss, Arthur
I publikationen Mol Cell (2017)

Monovalent and Multivalent Ligation of the B Cell Receptor Exhibit Differential Dependence upon Syk and Src Family Kinases

av Mukherjee, Sayak, Zhu, Jing, Zikherman, Julie, Parameswaran, Ramya, Kadlecek, Theresa A., Wang, Qi, Au-Yeung, Byron, Ploegh, Hidde, Kuriyan, John, Das, Jayajit, Weiss, Arthur
Publicerad 2013

An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor

av Shah, Neel H, Wang, Qi, Yan, Qingrong, Karandur, Deepti, Kadlecek, Theresa A, Fallahee, Ian R, Russ, William P, Ranganathan, Rama, Weiss, Arthur, Kuriyan, John
I publikationen eLife (2016)

The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway

av Goodfellow, Hanna Sjölin, Frushicheva, Maria P., Ji, Qinqin, Cheng, Debra A, Kadlecek, Theresa A., Cantor, Aaron J., Kuriyan, John, Chakraborty, Arup K., Salomon, Arthur, Weiss, Arthur
I publikationen Sci Signal (2015)

A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70

av Chan, Alice Y., Punwani, Divya, Kadlecek, Theresa A., Cowan, Morton J., Olson, Jean L., Mathes, Erin F., Sunderam, Uma, Man Fu, Shu, Srinivasan, Rajgopal, Kuriyan, John, Brenner, Steven E., Weiss, Arthur, Puck, Jennifer M.
I publikationen J Exp Med (2016)