טוען...
Switch-like activation of Bruton’s tyrosine kinase by membrane-mediated dimerization
The transformation of molecular binding events into cellular decisions is the basis of most biological signal transduction. A fundamental challenge faced by these systems is that reliance on protein–ligand chemical affinities alone generally results in poor sensitivity to ligand concentration, endan...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6561188/ https://ncbi.nlm.nih.gov/pubmed/31076553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819309116 |
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