Differences in flexibility underlie functional differences in the Ras activators Son of sevenless and Ras Guanine Nucleotide Releasing Factor 1

Por Freedman, Tanya S., Sondermann, Holger, Kuchment, Olga, Friedland, Gregory D., Kortemme, Tanja, Kuriyan, John
Publicado em 2009

Inhibition of Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full T cell receptor signaling

Por Xim Tan, Ying, Manz, Boryana N., Freedman, Tanya, Zhang, Chao, Shokat, Kevan M., Weiss, Arthur
Publicado em 2013

A Ras-induced conformational switch in the Ras activator Son of sevenless

Por Freedman, Tanya S., Sondermann, Holger, Friedland, Gregory D., Kortemme, Tanja, Bar-Sagi, Dafna, Marqusee, Susan, Kuriyan, John
Publicado em 2006

Stim1, PKCδ and RasGRP proteins set a threshold for pro-apoptotic Erk signaling during B cell development

Por Limnander, Andre, Depeille, Philippe, Freedman, Tanya S., Liou, Jen, Leitges, Michael, Kurosaki, Tomohiro, Roose, Jeroen P., Weiss, Arthur
Publicado em 2011

ZAP-70: An Essential Kinase in T-cell Signaling

Por Wang, Haopeng, Kadlecek, Theresa A., Au-Yeung, Byron B., Goodfellow, Hanna E. Sjölin, Hsu, Lih-Yun, Freedman, Tanya S., Weiss, Arthur
Publicado em 2010

LynA regulates an inflammation-sensitive signaling checkpoint in macrophages

Por Freedman, Tanya S, Tan, Ying X, Skrzypczynska, Katarzyna M, Manz, Boryana N, Sjaastad, Frances V, Goodridge, Helen S, Lowell, Clifford A, Weiss, Arthur
Publicado no eLife (2015)