LynA regulates an inflammation-sensitive signaling checkpoint in macrophages

Clustering of receptors associated with immunoreceptor tyrosine-based activation motifs (ITAMs) initiates the macrophage antimicrobial response. ITAM receptors engage Src-family tyrosine kinases (SFKs) to initiate phagocytosis and macrophage activation. Macrophages also encounter nonpathogenic molec...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Freedman, Tanya S, Tan, Ying X, Skrzypczynska, Katarzyna M, Manz, Boryana N, Sjaastad, Frances V, Goodridge, Helen S, Lowell, Clifford A, Weiss, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626889/
https://ncbi.nlm.nih.gov/pubmed/26517880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09183
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