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A Ras-induced conformational switch in the Ras activator Son of sevenless
The Ras-specific guanine nucleotide-exchange factors Son of sevenless (Sos) and Ras guanine nucleotide-releasing factor 1 (RasGRF1) transduce extracellular stimuli into Ras activation by catalyzing the exchange of Ras-bound GDP for GTP. A truncated form of RasGRF1 containing only the core catalytic...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1629002/ https://ncbi.nlm.nih.gov/pubmed/17075039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608127103 |
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