Cargando...

Membrane-dependent Signal Integration by the Ras Activator Son of Sevenless

The kinetics of Ras activation by Son of Sevenless (SOS) changes profoundly when Ras is tethered to membranes, instead of being in solution. SOS has two binding sites for Ras, one of which is an allosteric site that is distal to the active site. The activity of the SOS catalytic unit (SOS(cat)) is u...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Gureasko, Jodi, Galush, William J., Boykevisch, Sean, Sondermann, Holger, Bar-Sagi, Dafna, Groves, Jay T., Kuriyan, John
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440660/
https://ncbi.nlm.nih.gov/pubmed/18454158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1418
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!