Expression and Function of Tec, Itk, and Btk in Lymphocytes: Evidence for a Unique Role for Tec

The Tec protein tyrosine kinase is the founding member of a family that includes Btk, Itk, Bmx, and Txk. Btk is essential for B-cell receptor signaling, because mutations in Btk are responsible for X-linked agammaglobulinemia (XLA) in humans and X-linked immunodeficiency (xid) in mice, whereas Itk i...

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Detalhes bibliográficos
Main Authors: Tomlinson, Michael G., Kane, Lawrence P., Su, Jennifer, Kadlecek, Theresa A., Mollenauer, Marianne N., Weiss, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC355844/
https://ncbi.nlm.nih.gov/pubmed/14993283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.6.2455-2466.2004
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