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Expression and Function of Tec, Itk, and Btk in Lymphocytes: Evidence for a Unique Role for Tec
The Tec protein tyrosine kinase is the founding member of a family that includes Btk, Itk, Bmx, and Txk. Btk is essential for B-cell receptor signaling, because mutations in Btk are responsible for X-linked agammaglobulinemia (XLA) in humans and X-linked immunodeficiency (xid) in mice, whereas Itk i...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC355844/ https://ncbi.nlm.nih.gov/pubmed/14993283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.6.2455-2466.2004 |
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