Laddar...
Rescue of the aggregation prone Itk Pleckstrin Homology domain by two mutations derived from the related kinases, Btk and Tec
IL-2 inducible T-cell kinase (Itk) is a Tec family non-receptor tyrosine kinase involved in signaling downstream of the T-cell receptor. Itk contains an amino-terminal Pleckstrin Homology (PH) domain that binds phosphatidylinositol (3,4,5)-trisphosphate, recruiting Itk to the plasma membrane upon T-...
Sparad:
| Huvudupphovsmän: | , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Wiley Subscription Services, Inc., A Wiley Company
2012
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3631358/ https://ncbi.nlm.nih.gov/pubmed/22761113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2114 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|