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T-Cell Signaling Regulated by the Tec Family Kinase, Itk
The Tec family tyrosine kinases regulate lymphocyte development, activation, and differentiation. In T cells, the predominant Tec kinase is Itk, which functions downstream of the T-cell receptor to regulate phospholipase C-γ. This review highlights recent advances in our understanding of Itk kinase...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890196/ https://ncbi.nlm.nih.gov/pubmed/20519342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a002287 |
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