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Identification of an allosteric signaling network within Tec family kinases

The Tec family kinases are tyrosine kinases that function primarily in hematopoietic cells. The catalytic activity of the Tec kinases is positively influenced by the regulatory domains outside of the kinase domain. The current lack of a full-length Tec kinase structure leaves a void in our understan...

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Detalhes bibliográficos
Main Authors: Joseph, Raji E., Xie, Qian, Andreotti, Amy H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949508/
https://ncbi.nlm.nih.gov/pubmed/20826165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.08.035
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