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Identification of an allosteric signaling network within Tec family kinases

The Tec family kinases are tyrosine kinases that function primarily in hematopoietic cells. The catalytic activity of the Tec kinases is positively influenced by the regulatory domains outside of the kinase domain. The current lack of a full-length Tec kinase structure leaves a void in our understan...

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Bibliografische gegevens
Hoofdauteurs: Joseph, Raji E., Xie, Qian, Andreotti, Amy H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949508/
https://ncbi.nlm.nih.gov/pubmed/20826165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.08.035
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