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SH2 dependent autophosphorylation within the Tec family kinase Itk
The Tec family kinase, Itk, undergoes an in cis autophosphorylation on Y180 within its SH3 domain. Autophosphorylation of the Itk SH3 domain by the Itk kinase domain is strictly dependent on the presence of the intervening SH2 domain. A direct docking interaction between the Itk kinase and SH2 domai...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722949/ https://ncbi.nlm.nih.gov/pubmed/19523959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.06.023 |
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