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Mechanism and functional significance of Itk autophosphorylation
Tec family non-receptor tyrosine kinases (Itk, Btk, Tec, Rlk and Bmx) are characterized by the presence of an autophosphorylation site within the non-catalytic Src homology 3 (SH3) domain. The full length Itk mutant containing a phenylalanine in place of the autophosphorylated tyrosine has been prev...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753204/ https://ncbi.nlm.nih.gov/pubmed/17897671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.08.060 |
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