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An autoinhibitory role for the Pleckstrin Homology domain of ITK and its interplay with canonical phospholipid recognition
Pleckstrin homology (PH) domains are well known as phospholipid binding modules yet evidence is mounting that PH domain function extends beyond lipid recognition. In the current work, we characterize a protein binding function for the PH domain of Interleukin-2-inducible tyrosine kinase (ITK), an im...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5956896/ https://ncbi.nlm.nih.gov/pubmed/28516764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01182 |
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