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An autoinhibitory role for the Pleckstrin Homology domain of ITK and its interplay with canonical phospholipid recognition
Pleckstrin homology (PH) domains are well known as phospholipid binding modules yet evidence is mounting that PH domain function extends beyond lipid recognition. In the current work, we characterize a protein binding function for the PH domain of Interleukin-2-inducible tyrosine kinase (ITK), an im...
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| Vydáno v: | Biochemistry |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5956896/ https://ncbi.nlm.nih.gov/pubmed/28516764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01182 |
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