Llwytho...

SH2 dependent autophosphorylation within the Tec family kinase Itk

The Tec family kinase, Itk, undergoes an in cis autophosphorylation on Y180 within its SH3 domain. Autophosphorylation of the Itk SH3 domain by the Itk kinase domain is strictly dependent on the presence of the intervening SH2 domain. A direct docking interaction between the Itk kinase and SH2 domai...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Joseph, Raji E., Severin, Andrew, Min, Lie, Fulton, D. Bruce, Andreotti, Amy H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722949/
https://ncbi.nlm.nih.gov/pubmed/19523959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.06.023
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